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xanthene <--> listnames
after reading janet raloff's latest in _science news_ i got curious on the
structure of xanthene, which chlorine substituted compound the article said
has been found in P&P effluent but had problems being differentiated in
elution from pcdd/f. i was thinking it was a one ring compound, perhaps
because i knew it is a biological molecule, but in fact it is C(13)H(10)O,
m.w. 188.22. my regular dictionary said it's found in urine ('xanth-' =
yellow in greek).
0
/ \ /\ / \
| | | |
\ / \ /\ / (messy! assume 2 aromatic rings & a bridge inbetween--not
three rings)
so, substitute an oxygen for the bottom C in the bridge to get a dioxin, or
eliminate it and get a furan. the point raloff was implying (by also
giving an example of a common brominated analog to tcdd w/ greater
toxicity), and that i want to make, is: 1) there are hundreds Ah binding
analogs and other substitutes for chlorinated Ah binding pcdd/f/pcb's. 2)
there are other receptors thousands of other persistant & bioaccum.
molecules can bind to, many non-chlorinated and non-halogenated. i believe
sulfur substituted analogs to pcdd/f are of some concern, for example.
so, 3) i propose a merger of wash. toxics coaltn's endohealth list,
sierra's consequence-env.-hormones list and cchw's dioxin-l. sierra has
the more descriptive name and larger traffic than wtc's, but cchw was
there first and seems to be the largest (as a result of age?). anyway, this
may be a non-starter for any number of reasons, but i think one major
synnergy would be that more concerned parties could be put in touch w/ more
posted information, by merging subscribers. smaller advantages include not
missing information, easier posting of information.
tony tweedale