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what are calcium channel blockers?
>what are calcium channel blockers? Are ordinary calcium supplements in this
>>At 11:43 17/10/97 -0400, Tony Tweedale wrote:
>> "Calcium Channel Blockers May Raise [breast] Cancer Risk
>>[Findings]." Washington Post, 16 October 97, A8.
i wanted to take a stab at this despite being eminetly UNqualified, becasue
i just happened yesterday to be reading the intro articles from an '89
niehs symposia on [Ca2+]i (intracellular calcium ion concentrations)
toxicicology. aside from the item above, my recent post on 'evolution of
Ah receptor' mentions calcium upset caused by oxidative damage.
i never realized calcium biology was so ubiquitous! for one, it serves as
a hormone w/ regular protein receptors to transduce a multitude of messages
and to maintain Ca homeostasis (in fact, these are the 2 broad functions
of calcium, but it's major applications in the body seem to number in the
dozens). so the breast cancer connection may have to do w/ the multitude
of steps in Ca/receptor activties.
to get to your Q., a major role of Ca is in cell membrane passage (in &
out). heavy metal competitors to Ca for binding to proteins involved in Ca
channel activities are one category of blockers, i believe i read. all i
know about dietary Ca supplements is that one form is effective for bone
density, another not.