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ramazzini strikes again! hormone <--> breast cancer connection
ramazzini strikes again!
also, the may '97 _ehp_ mentions that a g.t. beatson in _lancet_, 1898--one
hundred years ago--noted that ovarectomized women get less breast cancer.
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FOR IMMEDIATE RELEASE NIEHS Contact: Tom Hawkins
April 29, 1997 919/541-1402
NIEHS PR #8-97 919/782-3009
JOURNAL EXPLORES HORMONES, ENVIRONMENT AND BREAST CANCER
----------------------------------------------------------------------------
The influence of hormones, hormone metabolism and environmental hormones on
breast cancer is the subject of the April Environmental Health Perspectives
Supplements (Volume 105, Supplement 3) of the National Institute of
Environmental Health Sciences.
Although it begins with a note that knowledge of a relationship between
hormones and breast cancer is more than 200 years old, the issue contains
the most current research, in papers updated from a workshop at the Center
for Bioenvironmental Research at Tulane/Xavier University in New Orleans.
The volume was edited by Devra Lee Davis, Ph.D., a scientist with the World
Resources Institute in Washington, D.C.
Any member of the media can obtain a copy of this comprehensive survey of
current breast cancer research by calling Tom Hawkins, at (919) 541-1402, or
Bill Grigg at (919) 541-2605.
In a co-authored introduction to the issue, Dr. Davis and Susan M. Sieber,
Ph.D., of the National Cancer Institute, write:
"For more than 200 years, scientists have appreciated that breast cancer
cannot arise without hormonal influences. In the 18th Century, the
pioneering researcher on environmental medicine, Barnardo Ramazzini,
observed that nuns had higher rates of breast cancer and speculated that
this might be tied to the fact that they did not have children."
Today hormonal influences that are of concern in breast cancer include
exposures to endocrine-disrupting environmental chemicals.
The journal supplement compiles 22 presentations under four section
headings: Hormonal Metabolites as Biologic Markers and Breast Cancer Risk;
Human Studies on Hormonal Metabolism and Breast Cancer; Effects of
Environmental Exposures on Estrogenic Activity; and Establishing the Risks
from Xenohormones.
###
PLANNING AHEAD: The fourth in a series of NIEHS/National Toxicology Program
conferences on environmental estrogens, Estrogens in the Environment IV:
linking fundamental knowledge, risk assessment and public policy will be
held July 20-23 at the Crystal Gateway Marriott, Arlington, Va., bringing
together basic scientists and policy makers to assess the public health
impact of these environmental estrogen exposures. For information, contact
the NTP Liaison and Scientific Review Office (919) 541-0530.
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tony tweedale