[Pharm-policy] How much conflict of interest in academic research?

[James Love]

Read the text below to see how much conflict of interest there is for
the authors of this paper on the use of a drug for depression.  Jamie

http://www.nejm.org/content/2000/0342/0020/1462.asp

The New England Journal of Medicine -- May 18, 2000 -- Vol. 342, No. 20 
 
A Comparison of Nefazodone, the Cognitive Behavioral-Analysis System of
Psychotherapy, and Their Combination for the Treatment of Chronic
Depression


>From the Department of Psychiatry, Brown University, Providence, R.I.
(M.B.K.); the Unipolar Mood Disorders Institute, Department of
Psychology, Virginia Commonwealth University, Richmond (J.P.M.); the
Department of Psychology, State University of New York at Stony Brook,
Stony Brook (D.N.K.); the Department of Psychiatry and Behavioral
Sciences, Stanford University, Stanford, Calif. (B.A.); the Department
of Psychiatry and Behavioral Sciences, University of Washington, Seattle
(D.L.D.); the Department of Psychiatry, University of Arizona, Tucson
(A.J.G.); the Department of Psychiatry, Cornell University Medical
College, New York (J.C.M.); the Department of Psychiatry, Emory
University School of Medicine, Atlanta (C.B.N.); the Department of
Psychiatry and Behavioral Sciences, University of Texas Medical Branch
at Galveston, Galveston (J.M.R.); the Department of Psychiatry, Western
Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh
(M.E.T.); the Department of Psychiatry, University of Texas Southwestern
Medical Center at Dallas, Dallas (M.H.T.); and the Department of
Psychiatry, Rush-Presbyterian-St. Luke's Medical Center, Chicago (J.Z.).
Address reprint requests to Dr. Keller at the Department of Psychiatry
and Human Behavior, Brown University, 345 Blackstone Blvd., Providence,
RI 02906. 

Supported by Bristol-Myers Squibb. Dr. Keller has served as a consultant
to or received honorariums from Pfizer, Bristol-Myers Squibb, Forest
Laboratories/Parke-Davis, Wyeth - Ayerst, Merck, Janssen, Eli Lilly,
Organon, and Pharmacia - Upjohn. He has received research grants from
Wyeth - Ayerst, SmithKline Beecham, Upjohn, Pfizer, Bristol-Myers
Squibb, Merck, Forest Laboratories, Zeneca, and Organon. He has served
on the advisory board of Wyeth - Ayerst, Pfizer, Bristol-Myers Squibb,
Eli Lilly, Forest Laboratories/Parke-Davis, Organon, SmithKline Beecham,
Merck, Janssen, Mitsubishi Pharmaceuticals, Zeneca, Scirex, and Otsuka.
Dr. Klein has served as a consultant to Bristol-Myers Squibb. Dr. Dunner
has served as a consultant to Bristol-Myers Squibb, SmithKline Beecham,
Glaxo Wellcome, and Eli Lilly. He has received research grants from
Bristol-Myers Squibb, Pfizer, Pharmacia - Upjohn, SmithKline Beecham,
Forest Laboratories, Glaxo Wellcome, and Wyeth - Ayerst. He has received
speaker's honorariums from Bristol-Myers Squibb, SmithKline Beecham,
Glaxo Wellcome, Eli Lilly, Organon, and Wyeth - Ayerst. Dr. Gelenberg
has received grants and research support from Bristol-Myers Squibb,
Organon, Pfizer, Lilly Research Laboratories, Janssen, Merck Sharp &
Dohme, SmithKline Beecham, Wyeth - Ayerst, Hoechst Marion Roussel, and
Forest Laboratories. He has been a member of speakers' bureaus sponsored
by Bristol-Myers Squibb, Pfizer, SmithKline Beecham, Janssen, Lilly,
Forest Laboratories, and Parke-Davis. He is a stockholder or has other
ownership interest in Pfizer, Warner-Lambert, and Eli Lilly. He has
served as a consultant to Eli Lilly, Scios, Forest Laboratories,
Parke-Davis, Pfizer, Janus Pharmaceuticals, Best Practice, and
Bristol-Myers Squibb. Dr. Markowitz has received speaker's honorariums
from Bristol-Myers Squibb, Eli Lilly, Forest Laboratories, Organon, and
Pfizer. Dr. Nemeroff has been a consultant to or received honorariums
from Abbott, AstraZeneca, Bristol-Myers Squibb, Forest Laboratories,
Janssen, Eli Lilly, Merck, Mitsubishi, Neurocrine Biosciences, Organon,
Otsuka, Pfizer, Pharmacia - Upjohn, Sanofi, SmithKline Beecham, Solvay,
and Wyeth - Ayerst. He has received research support from Abbott,
AstraZeneca, Bristol-Myers Squibb, Forest Laboratories, Janssen, Eli
Lilly, Organon, Pfizer, Pharmacia - Upjohn, SmithKline Beecham, Solvay,
and Wyeth - Ayerst. Dr. Russell has been a consultant to or received
honorariums from Abbott, Bristol-Myers Squibb, Janssen, Eli Lilly,
Pfizer, and Quintiles. He has received research support from Abbott,
Bristol-Myers Squibb, Eli Lilly, Parke-Davis, Pharmacia - Upjohn,
Pfizer, SmithKline Beecham, Wyeth - Ayerst, Shire, and Quintiles. Dr.
Thase has served as a consultant to Bristol-Myers Squibb, Eli Lilly,
Forest Laboratories, Glaxo Wellcome/Cerenex Pharmaceuticals, Merck,
Organon, Pfizer, Pharmacia - Upjohn, and Wyeth - Ayerst. He has received
grant and research support from Bristol-Myers Squibb, Lipha
Pharmaceuticals, Merck, Organon, Pharmacia - Upjohn, and Wyeth - Ayerst.
He has been a member of speakers' bureaus sponsored by Bristol-Myers
Squibb, Eli Lilly, Forest Pharmaceuticals, Glaxo Wellcome/Cerenex
Pharmaceuticals, Organon, Parke-Davis, Pfizer, Pharmacia - Upjohn,
SmithKline Beecham, Solvay, and Wyeth - Ayerst. Dr. Trivedi has received
research grants from Abbott, Akzo (Organon), Bayer, Bristol-Myers
Squibb, Eli Lilly, Forest Laboratories, Glaxo Wellcome, Janssen, Johnson
& Johnson, MeadJohnson, Parke-Davis, Pfizer, Pharmacia - Upjohn, Solvay,
and Wyeth - Ayerst. He has been a member of speakers' bureaus sponsored
by Bristol-Myers Squibb, Forest Laboratories, Pharmacia - Upjohn,
Solvay, and Wyeth - Ayerst. Dr. Zajecka has received grants and research
support from Abbott, Bristol-Myers Squibb, Eli Lilly, Glaxo Wellcome,
Organon, Otsuka America, Parke-Davis, Pfizer, Pharmacia - Upjohn, and
Sanofi Research. He has served as a consultant to or has served on the
advisory board of Abbott, Bristol-Myers Squibb, and Eli Lilly. He has
been a member of speakers' bureaus sponsored by Abbott, Bristol-Myers
Squibb, Eli Lilly, Pfizer/Roerig, SmithKline Beecham, Upjohn, and Wyeth
- Ayerst. Dr. Blalock has served as a consultant to Bristol-Myers
Squibb. Dr. DeBattista has been a member of speakers' bureaus sponsored
by Abbott, Bristol-Myers Squibb, Eli Lilly, Forest Laboratories, Glaxo
Wellcome, Parke-Davis, Pfizer, Scios, SmithKline Beecham, Wyeth -
Ayerst, and Organon. He has received grants and research support from
Abbott, Bristol-Myers Squibb, Eli Lilly, Forest Laboratories, Glaxo
Wellcome, Pfizer, the National Alliance for Research on Schizophrenia
and Depression, Pharmacia - Upjohn, PharmaPrint/ABA, SmithKline Beecham,
and Wyeth - Ayerst. He has served as a consultant to Bristol-Myers
Squibb, Eli Lilly, Glaxo Wellcome, and PharmaPrint. Dr. Fawcett has
received grants and research support from Abbott, Bristol-Myers Squibb,
Glaxo, Eli Lilly, Organon, Pfizer, SmithKline Beecham, Wyeth - Ayerst,
and Zeneca. He has served as a consultant to Abbott, Bristol-Myers
Squibb, Eli Lilly, EM Industries, Forest Laboratories, Glaxo Wellcome,
Pfizer, Pharmacia - Upjohn, and SmithKline Beecham. He has been a member
of speakers' bureaus sponsored by Abbott, Bristol-Myers Squibb, Eli
Lilly, Pfizer/Roerig, Pharmacia - Upjohn, SmithKline Beecham, and Wyeth
- Ayerst. Dr. Hirschfeld has received grants and research support from
Abbott, Bristol-Myers Squibb, Organon, and Pfizer. He has served as a
consultant to or on the advisory board of Abbott, Bristol-Myers Squibb,
Glaxo Wellcome, Forest Laboratories, Eli Lilly, Pfizer, SmithKline
Beecham, Janssen, Organon, Parke-Davis, and Pharmacia - Upjohn. Dr.
Kocsis has had research contracts with Bristol-Myers Squibb, Pfizer,
Forest Laboratories, Eli Lilly, and Wyeth - Ayerst. He has received
speaker's honorariums from Bristol-Myers Squibb, Forest Laboratories,
and Eli Lilly. He owns stock in Pfizer and Forest Laboratories. Dr.
Kornstein has received research grants from Bristol-Myers Squibb,
Pfizer, Eli Lilly, Glaxo Wellcome, Forest Laboratories, Mitsubishi
Pharmaceuticals, and Biovail. She has served as a consultant to
Bristol-Myers Squibb, Pfizer, Eli Lilly, and Pharmacia - Upjohn. She has
received honorariums from Bristol-Myers Squibb, Pfizer, and Glaxo
Wellcome. Dr. Ninan has received grants and research support from
Abbott, Bristol-Myers Squibb, Eli Lilly, Forest Laboratories, Organon,
Pharmacia - Upjohn, SmithKline Beecham, and Solvay. He has served as a
consultant to Pfizer, TAPPharma, and Wyeth - Ayerst. He has been a
member of speakers' bureaus sponsored by Abbott, Bristol-Myers Squibb,
Eli Lilly, Forest Laboratories, Organon, Parke-Davis, Pfizer, Pharmacia
- Upjohn, SmithKline Beecham, Solvay, Janssen, and Wyeth - Ayerst. Dr.
Rothbaum has served as a consultant to Bristol-Myers Squibb and Pfizer.
She has been a member of the advisory board of and a speakers' bureau
sponsored by Pfizer. Dr. Rush has received grants and research support
from Abbott, Bristol-Myers Squibb, Cyberonics, Eli Lilly, Forest
Laboratories/Parke-Davis, Glaxo Wellcome, Janssen, Novartis, Organon,
Pfizer, Pharmacia - Upjohn, SmithKline Beecham, Wyeth - Ayerst, and
Zeneca. He has served as a consultant to Bristol-Myers Squibb,
Cyberonics, Eli Lilly, Forest Laboratories/Parke-Davis, Glaxo Wellcome,
Janssen, Merck, Organon, Pfizer, Pharmacia - Upjohn, and Wyeth - Ayerst.
He has been a member of speakers' bureaus sponsored by Abbott,
Bristol-Myers Squibb, Cyberonics, Eli Lilly, Forest
Laboratories/Parke-Davis, Glaxo Wellcome, Organon, Pfizer, Pharmacia -
Upjohn, and Wyeth - Ayerst. Dr. Schatzberg has served as a consultant to
or received honorariums from Abbott, Bristol-Myers Squibb, Corcept
Therapeutics, Forest Laboratories, Janssen, Eli Lilly, Merck, Mitsubishi
Pharmaceuticals, Organon, Parke-Davis, Pfizer, Pharmacia - Upjohn,
Sanofi, Scirex, SmithKline Beecham, Solvay, and Wyeth - Ayerst. He has
received research support from Bristol-Myers Squibb, Pfizer, and
SmithKline Beecham. He has equity ownership in Corcept, Merck, Pfizer,
and Scirex. 

We are indebted to Drs. Jack E. Carr, Pedro L. Delgado, Frank Dowling,
Gregory Eaves, Robert H. Howland, and Carina Vocisano for assisting with
the study. 



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James Love, Consumer Project on Technology    
P.O. Box 19367        | http://www.cptech.org 
Washington, DC 20036  | love@cptech.org       
Voice 202/387-8030    | Fax 202/234-5176     
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