[Dioxin-l] molecular mechanism of dioxin action

[Jon Campbell]

In the paper I cited (actually it was David's cite) it was not clear that
the AhR that was attached to the dioxin which degraded; the implication I
saw was that the dioxin had bound it so tightly and permanently that the
number of AhR sites for the cell became diminished. But then I'm not a
biologist, so I might have missed something in the cite.

Jon

-----Original Message-----
From: Tony Tweedale [mailto:ttweed@wildrockies.org]
Sent: Wednesday, February 16, 2000 8:58 PM
To: dioxin-l@venice.essential.org
Subject: RE: [Dioxin-l] molecular mechanism of dioxin action


>From: "david bell" <burnt_paper@hotmail.com>
>
>These papers do not address your other statement- that transcription
>initiated by dioxin continues- but the disappearance of AhR from the
nucleus
>suggests that the converse is true. However, it is quite clear, that in the

david or anyone:  why would this be the case--can't TCDD alone (or TCDD
complexed w/ anything else but sans AHR), stay glommed onto chromosones?
What does the literature say, if anything (or did I miss something
pertinent that ws already posted)?




_______________________________________________
Dioxin-l mailing list
Dioxin-l@lists.essential.org
http://lists.essential.org/mailman/listinfo/dioxin-l