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Letter on Potential Effect of VIRAMUNE (nevirapine) on Methadone.




FYI--

Boehringer Ingelheim notifies health professionals about the potential
effect that VIRAMUNE (nevirapine) may have in patients taking chronic
methadone maintenance therapy.  VIRAMUNE may decrease  plasma concentrations
of methadone by increasing its hepatic metabolism.  A copy of the letter may
be found at: http://www.fda.gov/medwatch/safety/1999/viramu.html and in PDF
format at: http://www.fda.gov/medwatch/safety/1999/viramu.pdf

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