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SCMP Series Part III (fwd)



            Monday  January 18  1999

                The Cigarette Papers 
                   John Bacon-Shone 

                     Emphatic rejections: Dr John Bacon-Shone 

                Leading scientist Dr John Bacon-Shone is one of a
                handful of key advisers to the highest levels of the
                Hong Kong Government on policy and strategic
                issues. The 42-year-old expert in statistics was
                appointed a full-time member of the Central Policy
                Unit in July last year, on secondment from his job
                as director of the Social Sciences Research Centre
                of the University of Hong Kong.

                His CV lists his work with scientific journals,
                conferences, consultancies and societies, including
                tobacco-funded and anti-smoking groups. In two
                interviews with the Post, Dr Bacon-Shone said he
                had never knowingly worked for the tobacco
                industry.

                He said he did not know at the time that the
                tobacco industry was paying for him to attend
                symposiums on indoor air and passive smoking in
                Portugal, Canada and Thailand in 1990. He also
                emphatically rejected recent assertions by Philip
                Morris and one of its long-standing lawyers, John
                Rupp, that he (Dr Bacon-Shone) was always
                aware he was a paid consultant to the tobacco
                industry.

                Dr Bacon-Shone said he had always remained true
                to his ethical and scientific obligations to develop
                honest science and to distribute it openly,
                irrespective of funding.

                "To my knowledge I have never met anyone
                working for a tobacco company. To my
                knowledge, John Rupp was a lawyer for the
                funding source. I do not question where the funds
                come from. I ask 'is it ethical, is it advancing
                science and truth?' My conscience is clear. I have
                never done anything unethical.

                "I feel very strongly I have never done anything I
                should feel ashamed about. I agree violently that
                smoking is a serious health risk, that the tobacco
                industry can't be trusted and has lied, but as a
                scientist I think that passive smoking has been the
                subject of a lot of bad science."

                Dr Bacon-Shone said he had presented at a
                tobacco-sponsored conference in Lisbon a paper
                which questioned the findings of Japanese
                Professor Hirayama, who years earlier had found a
                high correlation between environmental tobacco
                smoke (ETS) and lung cancer in non-smokers.
                Professor Hirayama's findings were devastating for
                the tobacco industry. Dr Bacon-Shone said he was
                not paid for presenting his paper, which he agrees
                would have been "music to the ears" of the tobacco
                industry.

                "It would be unfortunate if there was the implication
                that it was contrived. But the key point is: does
                what I wrote stand up? Yes, it does, so I have no
                regrets on writing the paper. My position is clear:
                the evidence that tobacco is a health hazard is
                overwhelming, but the work by Professor Hirayama
                and others overstated the risk of ETS and that's a
                scientific issue. That's why I was happy to write the
                study on Hirayama.

                "ETS is a health hazard, but let's be frank - one of
                the major reasons people want to get rid of it is that
                it's so obnoxious. But we should not try to use
                biased findings based on science that is not of the
                finest quality to drive the policies we desire. If we
                allow the ends to justify the means, where do we
                stop?

                "Any industry that thinks the risk of their product is
                overstated by poor research clearly has an interest
                to address that and I think there's nothing unethical
                in doing that. If someone asked me to do a study
                and said 'we will decide whether to publish or not',
                then I would not do it. But if someone offers me
                money to present my research somewhere, then I
                think it's perfectly ethical for me to present it -
                irrespective of the funding.

                "To me it makes no difference if the money comes
                from COSH (Council on Smoking and Health) or
                Philip Morris. The problem would be if you were
                only funded to do a certain kind of work, or if the
                results were unfavourable and could not be
                released.

                "The separate issue is whether the funding body
                should hide. Quite clearly, the tobacco industry was
                paying people to do certain things and they had a
                PR mechanism [to promote those things]. It's
                unethical for them not to reveal who the ultimate
                funding source is.

                "They have clearly used the research that we did to
                try to push a particular line. The main unethical
                point was simply hiding. They hid lots of things. I'm
                very unhappy about the implications that I'm a
                stooge. Nobody was paying me to do something
                that I did not already feel. I'm sure that they picked
                on all of us because they felt we would take a
                particular independent line."

                Dr Bacon-Shone said the tobacco documents and
                their allegations of his involvement were distressing.
                "I think that clearly, this shows [scientists] need to
                be more wary and not always believe everything
                you're told."
       

                       Copyright ©1998 South China Morning Post Publishers Ltd.
                                     All Rights Reserved. 

              
                           Monday  January 18  1999

                The Cigarette Papers 
                          Linda Koo 

                                                    

                           'Unaware': Dr Linda Koo 

                By researching and publishing a number of studies
                relating to dietary factors in lung cancer, Dr Linda
                Koo Chih-ling was known to tobacco industry
                scientists and chiefs as early as the mid-1980s.
                Internal company memos and documents refer to
                her work as a researcher in the University of Hong
                Kong's department of community medicine and in
                the Hong Kong Anti-Cancer Society, as well as her
                collaboration for several years with Swedish
                scientist Dr Ragnar Rylander.

                Dr Koo's studies found a high rate of lung cancer
                among children and women in Southern China and
                Hong Kong who had never smoked, suggesting that
                indoor pollution and diet were the biggest factors.
                Her published papers from the 80s include, Is
                Passive Smoking An Added Risk Factor For Lung
                Cancer In Chinese Women? and Measurements Of
                Passive Smoking And Estimates Of Lung Cancer
                Risk Among Non-Smoking Chinese Females.

                Dr Koo, whose work at the university was
                complicated by a plagiarism case she won against
                colleague Dr T H Lam, is now working at the
                American Health Foundation in New York and
                studying prostate and lung cancer.

                She told the Post she had never been a paid
                consultant to the tobacco industry. She said she
                was unaware that Professor Rylander, with whom
                she met several times in Hong Kong and abroad,
                was one of the tobacco industry's highest-paid
                consultants, receiving US$150,000 a year in the
                early 90s.

                "The point is if I'm doing work with Ragnar and if
                I'm happy with my work for him, that's OK. Who is
                he working with? That's none of my business.

                "I don't go round asking people their financial
                sources. I knew he did lots of work on air pollution.
                We are clear on our own agenda. Let's get the
                politics out of this. This is not the Middle Ages. It's
                not the Inquisition. The more the politics, the less
                the science. Too many people have gone
                overboard about ETS. It's no different from burning
                a leaf. I mean, tobacco is just a leaf.

                "The point is this - there are forces on all sides. For
                active smoking, it's quite clear there's a link with
                lung cancer. Passive smoking is a much more fuzzy
                issue, there's a lot of politics mixed up in the
                science. It's not like cavorting with the devil to meet
                people from the tobacco industry. We have to get
                the hysterics out of this. I'm a scientist. I can't be
                selective about who I will speak to. We have to
                deal with lobbyists all the time. We stick to what
                our research indicates. As a scientist, our integrity is
                bound up in presenting the data as shown. We will
                all be judged by time."

                Dr Koo said she attended some indoor air
                conferences. "I know that at some of the
                conferences, there was some [tobacco] industry
                money involved. That's nothing new. But we were
                certainly not paid to say that smoking is wonderful.
                I get invited to conferences all over the world. You
                would be paid an honorarium for speaking. An
                honorarium is a fee that's paid for a lecture. I don't
                consider that as being a paid consultant. I believe a
                paid consultant would be someone who has a
                contract to do a research project. We did not get
                huge amounts of money [for attending conferences].
                I'm sorry, a few hundred dollars would not buy me
                off. I certainly did not have meetings with [tobacco
                industry figures] saying 'you would do this or do
                that'. They knew my door was open. I do research
                they are interested in and I have a line they find very
                politically satisfying. As a scientist I give information
                out. I was not being paid."

                Dr Koo said she regretted that a confidential letter
                she wrote in 1988 to Y Y Tang, then of the
                Tobacco Institute, had ended up in the Philip
                Morris' archives and been made public. The
                two-page letter from Dr Koo pinpoints specific
                weaknesses in a study and report by Dr T H Lam
                on passive-smoking risks.

                "I was not paid for that, it was just my opinion,"
                said Dr Koo.

                "In terms of ETS, [tobacco companies] would be
                interested in my studies but that doesn't mean I was
                funded by them. There were findings they would
                have been happy with. We were working since
                1980 on why there was a high rate of lung cancer in
                non-smoking Chinese women, looking at all
                possible sources of pollutants, and we found no
                relationship to ETS.

                "In any case, I think whoever is putting up money
                for research, it helps expand the picture. I don't
                think because something is paid for by someone, it
                is scientifically unrigorous. If people are falsifying
                data, then they will be shown up. Their results won't
                be repeated."

                Dr Rylander told the Post from Sweden that he was
                a scientific adviser rather than a consultant to the
                tobacco industry and that he told Dr Koo: "Don't
                touch that money." He said Dr Koo probably
                would not have known he regularly informed Philip
                Morris about various aspects of Dr Koo's work in
                Hong Kong.
                                                     


                                                              I mean,
                                                             tobacco is
                                                             just a leaf