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Chitosan (XiDuoAn)-- the sixth element of human being



Chitosan (XiDuoAn)-- the sixth element of human being

     Chitin was first discovered in 1811 by French scientist Blakara, and in 1823 it was first 
purified from the cuticle of arthropod animal.   Chitin exists widely in the cell of low forms 
of life, such as bacteria, algae, the cuticle of arthropod animals (locust, shrink insect and 
etc.), and the cellwall of plants .It was lately recognized for its abundant resources in 
nature and was synthesized more than 1000 thousand million tones in nature each year.
Its chemical structure is very similar with cellulose, which is the polymer of hexose. The 
basic unit of cellulose is glucose. Whereas that of chitosan is N-acetyl-D-glucosamine 
(GlcNac) with ¦Â-1,4 linkages. Because it was purified from various species of arthropod and 
has similar structure of cellulose, it was called animal cellulose.
In past, one can absorb a little chitin from insect-like species in diets, but with the using 
of insecticide to kill pests, one can't get them in diets now, which was caused by the lackage 
of insect-like species being killed, thus resulting in the destroy of biological chain. 
Besides these, the pollution of surroundings and heavy metal lead to human being's diseases 
becoming stranger and more incurable. Meanwhile one is easier to get ill when he is still 
young. All these problems make many scientists in the world take serious thinking about such 
problems and hope to find out the solutions. Chitin probably can solve such problems. Now it 
is used in many fields, especially in health care, in which it shows five main functions: 
Strength the immunity of human being, Inhibit human's becoming older, Prevent being ill, 
Improve human's recovery, Adjust body's physiological action. XiDuoAn is verified to be 
helpful in health care by adjusting body's immunity and improving the resistance of human 
body, which was clearly stated in the instrument of ratification(Number 080 ,1997 ) of the 
Ministry of Public Health of China.

    1) INTRODUCTION
      Chitosan is a kind of powder-like food with colorless, nonpoison and tasteless. It is 
insoluble in water, but soluble in dilute acid(for example, acid in stomach) , lecithin in 
milk and many enzymes in cells. Being soluble,it looks like gel .It can be hydrolyzed into 
oligo-polymer, especially, when it is composed with six GlcNac, it shows the strongest 
physiological ability.
     Chemical structure:It is a high molecular weight(M.W.) materials ,M.W. is beyond 1000 
thousand. It is a (1¡ú4)-¦Â-linked linear polymer of 2-acetamindo-2-deoxy-D-glucose(i.e. 
N-acetylglucosamino) residues. Because of amino groups in its structure, it is alkali in water 
and shows to be positive ion groups in solution.
    2) Chitosan's functions in the body
    1.  Strength the body's immunity: Strength body's protection, Improve the ability of being 
recognized, Prevent harmful factors.
Anticancer:attack cancer cell directly, activate body's protection , kill abnormal cells and 
inhibit their growth; when it is used with other drugs, it can improve anticancer effect, 
lessen complication and side-effect.
    1.1  Inhibit transfer of cancer cell: there are about 100 thousand types of drugs, among 
which only a few are used in curing cancer and none is sure to inhibit transfer of cancer 
cell; Now chitosan is verified to be able to inhibit cancer's transfer. Why? Because chitosan 
can not only inhibit blood capillary inner cell's growth, but also conjugate "attachment 
molecular", which is usually conjugated by cancer cell, now chitosan conjugates it and block 
cancer's further conjugation. In this way chitosan inhibit cancer'            
    1.2   Activate human cell's function, prevent some diseases gotten from being older, 
prolong one's life.Why? Because chitosan can conjugate harmful oxygen ion, which is harmful to 
the normal cell by destroying them. Thus chitosan  can detoxicate such harmful ions, then 
makes people live longer.
    1.3   Eliminate harmful materials produced in the inside and outside of the body, strength 
self-curing ability and promote people's recovery.
    1.4   Adjust the body to maintain the balance of the body and prevent disease.
    1.5   Adjust body's physiological functions
    1.6   Maintain body's blood in normal pH(7.4) .Generally, tissue fluid between organs is 
easily changed from neutral to acid because of  carbon dioxide flowing from organs, which will 
make body's immunity become weaker  and cause people easier to be ill .Here  chitosan combine  
with hydroxide ion and cause blood in normal level.
    1.7   Maintain the normal cycle of  lymphatic fluid to excrete waste materials.
    1.8   Improve secretion of sex hormone ,help to make people become younger , at the same 
time improve one's looks and moisten one's skin.
So chitosan is such good foods that it can cure human by activating people's immunity, which 
can thoroughly improve people's own ability to cure and prevent all kids of disease caused by 
people's weak resistance to many viruses and harmful factors. That means : Chitosan can solve 
many chronic disease that can't be cured by modern medical technology which mainly aims at  
curing  people through their organs. Due to such different ways, chitosan can adjust body's 
cell in the whole view and improve people's own immunity. So it was called "functional food"

    3) Chitosan's  clinical  usage:
 1  Anticancer
   1.1  Activate lymphatic cell to kill cancer cell;
   1.2  Inhibit blood capillary inner cell's growth in cancer tissues, prevent cancer to 
diffuse;
   1.3  Inhibit  toxins in cancer cell,increase appetite to eat and strength one's body;
   1.4  Inhibit cancer cell's transfer;
 2 Improve curative effect while using with many special methods:
   2.1  Having had an operation in his early cancer, one may get    hauma; chitosan can help 
people to self-cure, adjust viscera's function and promote people's recovery from disease.
   2.2  Combined chitosan with the usage of radiotherapy or chemotherapy ,drugs can get better 
effect than using alone. For example, if 5-FU was covalent with chitosan ,the curative effect 
is four times larger than using 5-FU alone, which means they can corporate with each other in 
curing cancer.
   2.3  Chitosan can eradicate  poisonous materials produced in radiotherapy-free group,  also 
eradicate poisonous materials produced from chemotherapy drugs' metabolism in the body  and 
obviously relieve patient's pain caused by poison and side-effect in drug's curing cancer.
   2.4  Relieve patient's pain in his late cancer and make them feel comfortable for being 
dead , which will make their families feel a little console .
  3 Reduce high blood-pressure
   It is generally thought that original high blood-pressure is mainly concerned with sodium 
ion in salt, but now scientists find out that it is really concerned with chloral ion, and it 
is verified to activate blood vessel angiotensin transferase (ACE), then ACE change 
angiotensin1 into angiotensin2, which results in the contraction of blood vessel and cause 
blood-pressure become higher. Here chitosan  carry positive ion and it can combine chloral 
ions, then excrete them out.
  4 Reduce cholesterol, prevent cardiovascular system disease.
   Chitosan can adjust cholesterol in normal level ,thus prevent and cure atherosclerosis and 
various kinds of cardiovascular system disease .Its functions are below:
  4.1 Chitosan can excrete cholic acid by combining it first, which can decrease the amount of 
cholesterol absorbed by the body, in this way it further hamper the adsorption of fat and 
reduce blood-fat's level;
  4.2 Chitosan functions in two ways: chitosan can increase and strength the function of HDL ( 
high dentistry lipoprotein ), which is able to prevent atherosclerosis and have a normal 
function in metabolism . On the other hand ,because of  its carrying positive charge, it can 
combine LDL ( low dentistry lipoprotein ) and excrete it out. Through these two ways, chitosan 
can relieve disease in liver ,reduce blood-fat and prevent atherosclerosis.
  5 Reduce blood-sugar
  The body fluid of diabetes is normally acid, which lessen the functions of insulin and cause 
patient become more serious ( malignant cycle ). Here chitosan can make body fluid become 
alkali and improve the usage of insulin. Furthermore chitosan can adjust internal system to 
activate pancreas in secreting insulin,thus help to control diabetes. Especially diabetes in 
adult is mainly concerned with fat ,and fat makes people insensitive to the signals. chitosan 
can prevent diabetes through preventing fat by excelling more sugar.
  4) Strength liver's functions
  Liver is the largest gland in the body and has many functions , such as, maintain of normal 
metabolism, excel of waste materials ,biological transaction, secretion and etc. so it is very 
important to protect liver.
Reduce cholesterol and fat, prevent fatty liver and hepatitis.
Promote body to produce antibody of hepatitis virus. If used with interferon, it can get 
better curative effect.
Activate the function of aldehyde dehydrogenase in liver, which can detoxicate the 
intoxication of alcohol in body to prevent alcohol to destroy liver.
  5) Adjust nervous and internal system in two ways.
  Chitosan can be lysised into N-aminoglucoamine ,which can stimulate vagus to be exciting 
,cause microartery to become larger and improve the cycle of nerve ending. All will cause 
organs in the body to become stronger, promote sex hormone to secrete and make people become 
younger and more healthy.
  6) Absorb poisonous materials in the body and cure many diseases caused by poisons
Combine heavy metals and excel them out. It is well known that heavy metals, such as Lead 
Mercury,Arsenic and etc. can cause many diseases concerned with pain, blood, liver, nerve 
sight and various kinds of cancer. At present time, no drugs can excrete heavy metals from 
body. Here chitosan can perform such works, why? In its molecular structure, there is 
hydroxide radical adjacent to the free amino groups, which can conjugate heavy metal ions to 
secrete them out.
  7) Strength Kidney's functions, activate body's natural ability to self-cure and improve 
chronic exhaustion of Kidney , uremia patient's many symptoms. Here chitosan help to eradicate 
residues left in blood which even can't be taken away by medical methods. Chitosan seems to be 
a good way to cure disease in Kidney.
For people who major in radioactive rays, CT, MRI, isotope ,nuclear investigations and 
patients who want to use radiotherapy to cure diseases , chitosan can cure and prevent such 
radiation sicknesses.
  8) Cure diseases caused by burn, scald, trauma. speed up patient's recovery     
  Man-made skin made from chitosan has strong affinity to body cell. it can be absorbed and 
not be protected by the body ,thus make skin grow easily; Promote body cell to be active and 
produce a lot of collagen to eliminate scar in skin after recovery. It also can prevent blood, 
stanch bleeding, relieve pain and secrete antibiotic and avoid infection. In these ways it can 
further prevent wound to bleed and later infections.

Below are Different Prices of Productions according to Different Functional Ingredients:

XiDuoAn Multiple: The price is 830RMB/100USD per bottle.( Production Number:JY001) ,has all 
functions above.

XiDuoAn ¢ñ: The price is 495RMB/60USD per bottle ( Production Number:JY002 ). Mainly prevent 
tumor and strength people's immunity and produced for those people who are related to tumor or 
cancer .For more details, see the first, sixth and seventh functions above.

XiDuoAn ¢ò: The price is 396RMB/48USD per bottle (Production Number:JY003). Mainly reduce 
blood-pressure, blood-fat and blood-sugar, Eliminate fatty liver, see the second,third, forth, 
fifth, sixth and seven functions above.

XiDuoAn ¢ó : The price is 297RMB/36USD per bottle (Production Number:JY004). Mainly used in 
daily health care and used in curing various types of diseases in digestive systems, see the 
fifth, sixth and eighth functions above.

For more details, please contact:
aaoaaaoa@jlonline.com
Huang