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new slimicide
- To: pulppaper@onenw.org, panna@panna.org, ncap@igc.apc.org, ncamp@igc.apc.org, acxgm@montana.edu, eschreder@watoxics.org, aero@desktop.org, tlange@nprc.desktop.org, wildcenter@wildrockies.org, handler@selway.umt.edu, gutsche@wildrockies.org, dioxin-l@essential.org
- Subject: new slimicide
- From: ttweed@wildrockies.org (Tony Tweedale)
- Date: Mon, 10 Nov 1997 10:08:32 -0600
sunday 9 nov. our paper ran a blurb about a new P&P slimicide being
lobbied for on capital hill (yes, that juxtaposition is why the blurb ran!)
as so benign it deserves approval in food packaging, not just registration
as a pesticide. here's what i found about it (a simple .gif file of the
chemical structure is attached (use jpeg or a more involved image viewer),
i hope it goes through ok). for those who can't open the file, the
structure of Tetrakis(hydroxymethyl) phosphonium sulfate (THPS, aka
'pyroset') is a complexed one, (nominally two) phosphorous cations
complexing 4 ethanol (2 carbon) chains (the -OH facing outwards & both P
complexes in turn complexed w/ a sulfate SO4 double charged anion (ea.
charge complexing one of the two of the 8 total ethanol -OH's). it's
soluble in water & dmso, but much less in alcohols (huh??), no data here
for sol. non-polar organics.
there is an anologue using chloride as the complexing anion, called THPC,
but since Cl- has only one neg. charge and i didn't see an image of the
molecule, i don't know how it's complexed.
well, this may be safer than heavy metal (e.g. mercury) or orgaonohalide
slimicides, tho to work as a slimicide it must have pretty broad spectrum
toxicity ... i haven't really looked at the accompanying tox. data, which
is not comprehensive. it has 4 current pesticide registrations granted
12/95, no cancelled ones. two are 35% a.i., two 75% a.i.
at the end i've included a snip from epa's green chemistry awards page, as
the blurb mentioned the slimicide had received one. in fact it was only
nominated (see the Albright & Wilson Americas Inc. line)--i think
nominations are pretty open ended, and outnumbered ~ 10:1 to the eventual
'96 winners.
note that our pals nominated/had nominated for a green (the color of Cl2) award:
Alliance for Environmental Technology (AET)
The Use of Chlorine Oxide, the Foundation of Elemental
Chlorine-Free Bleaching for Pulp and Paper, as a Pollution
Prevention Process
and:
anyone heard of this "DuCare" system--what industry's is it for? (reply to
lists):
DuPont Company
The DuCare "Zero Effluent" Recycle Chemistry System
The INFINITY Dyeing Process
NAFION Membrane Technology
tony tweedale
---
TOLCIDE 352C
Registration number: 033677- 00005
Company: ALBRIGHT & WILSON UK LIMITED
210-222 HAGLEY ROAD WEST
OLDBURY, WARLEY, WEST MIDLANDS B68 ONN,
UK
Contact: LOUISE E COLLETT
Contact Phone: 44 1214205446
Status: Active
Approval date: 19951206
Cancel date:
Cancel reason:
Product manager: Marshall Swindell -- (703)308-6341
Chemical(s):
35.0000 % of (129058)
Chemical Names:(Common Name, Synonym, Trade Names)
CAS REG. NO. 55566-30-8
TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULPHATE (THPS)
Questions about this product's data?
TOLCIDE PS355A
Registration number: 033677- 00006
Company: ALBRIGHT & WILSON UK LIMITED
210-222 HAGLEY ROAD WEST
OLDBURY, WARLEY, WEST MIDLANDS B68 ONN,
UK
Contact: LOUISE E COLLETT
Contact Phone: 44 1214205446
Status: Active
Approval date: 19951206
Cancel date:
Cancel reason:
Product manager: Marshall Swindell -- (703)308-6341
Chemical(s):
35.0000 % of (129058)
Chemical Names:(Common Name, Synonym, Trade Names)
CAS REG. NO. 55566-30-8
TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULPHATE (THPS)
Questions about this product's data?
TOLCIDE PS75
Registration number: 033677- 00003
Company: ALBRIGHT & WILSON UK LIMITED
210-222 HAGLEY ROAD WEST
OLDBURY, WARLEY, WEST MIDLANDS B68 ONN,
UK
Contact: LOUISE E COLLETT
Contact Phone: 44 1214205446
Status: Active
Approval date: 19951012
Cancel date:
Cancel reason:
Product manager: Marshall Swindell -- (703)308-6341
Chemical(s):
75.0000 % of (129058)
Chemical Names:(Common Name, Synonym, Trade Names)
CAS REG. NO. 55566-30-8
TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULPHATE (THPS)
Questions about this product's data?
TOLCIDE PS75LT
Registration number: 033677- 00007
Company: ALBRIGHT & WILSON UK LIMITED
210-222 HAGLEY ROAD WEST
OLDBURY, WARLEY, WEST MIDLANDS B68 ONN,
UK
Contact: LOUISE E COLLETT
Contact Phone: 44 1214205446
Status: Active
Approval date: 19960418
Cancel date:
Cancel reason:
Product manager: Marshall Swindell -- (703)308-6341
Chemical(s):
75.0000 % of (129058)
Chemical Names:(Common Name, Synonym, Trade Names)
CAS REG. NO. 55566-30-8
TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULPHATE (THPS)
Questions about this product's data?
---
| National Institute of Health Sciences | Database
IARC DataBase
[ IARC ] Tetrakis(hydroxymethyl) phosphonium sulfate
id: 1338
casno: 55566-30-8
name: Tetrakis(hydroxymethyl) phosphonium sulfate
nvol: 0
volume: 48
page: 95
formula: C8H24O12P2S
molecular weight: 406.28
melting point: 0.00
boiling point: 0.00
experimantal data of animals: 0
experimantal data of bacteria: 0
human data: 0
evaluation: 0
Maintained by the Division of Chem-Bio Informatics at the National
Institute of Health Sciences.
Sent questions and comments to: taka@nihs.go.jp
This WWW/SYBASE gateway is implemented using Genera.
Back to DCBI Database Server HOME PAGE
---
TR-296
Toxicology and Carcinogenesis Studies of
Tetrakis(hydroxymethyl)phosphonium sulfate (THPS)
(CAS No. 55566-30-8) and
Tetrakis(hydroxymethyl)phosphonium chloride (THPC)
(CAS No. 124-64-1) in F344/N Rats and B6C3F1 Mice
(Gavage Studies)
Chemical Formula:
3D Structure
Tetrakis(Hydroxymethyl)Phosphonium Sulfate
C8H24O12P2S
Tetrakis(Hydroxymethyl)Phosphonium Chloride
C4H12O4PCl
Toxicology and carcinogenesis studies of tetrakis(hydroxymethyl)phosphonium
sulfate
(THPS) and tetrakis(hydroxymethyl)phosphonium chloride (THPC) were
conducted because of
the widespread use of these chemicals as flame retardants in cotton
fabrics. THPS was
available as a 72% aqueous solution and THPC as a 75% aqueous solution.
Short-term gavage
studies with a range of doses were conducted first to identify toxic
effects and affected
sites and to determine doses for the 2-year studies. The doses selected for
the 14-day
studies ranged from 12.5 to 200 mg/kg THPS for rats and mice, 9.4 to 150
mg/kg THPC for
rats, and 18.8 to 300 mg/kg THPC for mice. Mortality and reduction in body
weight gain
occurred at the two highest doses in the 14-day studies. There was hind
limb paralysis in
some rats and mice dosed at the highest concentrations of THPS and THPC.
In the 13-week studies, doses of THPS ranged from 5 to 60 mg/kg in rats and
from 2 to 180
mg/kg in mice; doses of THPC ranged from 3.75 to 60 mg/kg in rats and from
1.5 to 135
mg/kg in mice. Mortality and reduction in body weight gain occurred at the
two higher doses
for both sexes and species. Vascular degeneration of hepatocytes or
hepatocellular necrosis
was a common histopathologic finding. Hind limb paralysis was noted in rats
and mice
receiving the highest dose of THPC, and axonal degeneration, characterized
by swollen axon
sheaths, missing or fragmented axons, and some proliferation of neurolemma
cells, was
observed in rats. These lesions were found in the sciatic nerve, dorsal
roots of the caudal
spinal nerves, and the tracts of the spinal cord, particularly in the
dorsal column of the
lumbar cord.
Two-year studies were conducted in F344/N rats by administering 0, 5, or 10
mg/kg THPS
or 0, 3.75, or 7.5 mg/kg THPC in deionized water by gavage to groups of 49
or 50 animals of
each sex, 5 days per week for 103 or 104 weeks. Groups of 49 or 50 B6C3F1
mice were
administered 0, 5, or 10 mg/kg THPS (each sex), 0, 7.5, or 15 mg/kg THPC
(males), or 0, 15,
or 30 mg/kg THPC (females).
Survival of male rats was reduced for the low dose (after week 102) and the
high dose
(after week 67) groups given THPS compared with that of the vehicle
controls; survival at
terminal kill was as follows: vehicle control, 28/50; low dose, 13/50; high
dose, 16/50.
Survival of the high dose group of female rats given THPC was lower after
week 70 than
that of the vehicle controls (survival at terminal kill: 37/50; 34/50;
21/50). Mean body
weights of rats dosed with THPS or THPC were comparable to those of the
vehicle controls.
There was no difference in survival or mean body weights between the
vehicle controls and
mice dosed with either THPS or THPC. No neurotoxicity or any other signs of
clinical
toxicity were observed.
A nonneoplastic effect common to 13-week and 2-year exposure to THPS or
THPC was an
increase in the incidence of hepatocellular lesions, primarily cytoplasmic
vacuolization.
The incidences of this lesion in the two-year studies were dose related for
all studies
except for the mice receiving THPS. Other lesions observed included focal
hyperplasia of
the adrenal medulla in high dose male mice given THPS and follicular cell
hyperplasia of the
thyroid gland in high dose female mice given THPC. The increased incidences of
hematopoietic system lesions observed in these studies were not considered
biologically
related to chemical exposure because the increases were marginal, no
dose-response
relationship was observed, and the incidences of these lesions are highly
variable in
untreated rats and mice.
The incidences of mononuclear cell leukemia in low dose male rats
administered THPS or
THPC were somewhat greater than those in the vehicle controls (THPS: 30/50;
36/50;
20/50; THPC: 19/50; 25/50; 16/50). Low dose male mice administered THPS had an
increased incidence of malignant lymphomas when compared with vehicle
controls (2/50;
9/50; 0/50). These marginal increases in the incidences of hematopoietic
system tumors
were not considered related to chemical exposure, since they were
significant only by the
life table tests and were not dose related.
THPC demonstrated no mutagenic activity in Salmonella typhimurium strains
TA98, TA100,
TA1535, or TA1537 with or without metabolic activation. Both THPS and THPC
induced
forward mutations in mouse lymphoma L5178Y cells without metabolic
activation; neither
was tested in the presence of S9. THPC increased the frequency of
sister-chromatid
exchanges and chromosomal aberrations in Chinese hamster ovary cells in the
presence and
absence of exogenous metabolic activation.
An audit of the experimental data was conducted for the 2-year studies of
THPS and THPC.
No discrepancies were found that influenced the final interpretations.
Under the conditions of these 2-year gavage studies, there was no evidence of
carcinogenicity of THPS in either sex of F344/N rats or B6C3F1 mice given 5
or 10 mg/kg.
There was no evidence of carcinogenicity of THPC in either sex of F344/N
rats given 3.75 or
7.5 mg/kg, in male B6C3F1 mice given 7.5 or 15 mg/kg, or in female B6C3F1
mice given 15
or 30 mg/kg.
Report Date: February 1987
NTIS# PB87-204137/AS
---
NTP CHEMICAL REPOSITORY (RADIAN CORPORATION, AUGUST 29, 1991)
TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULFATE
-IDENTIFIERS
===========
*CATALOG ID NUMBER: 001198
*CAS NUMBER: 55566-30-8
*BASE CHEMICAL NAME: HYDROXYMETHYLPHOSPHONIUMSULFATE,TETRAKIS-
*PRIMARY NAME: TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULFATE
*CHEMICAL FORMULA: C8H24O12P2S
*STRUCTURAL FORMULA: ((HOCH2)4P)2.SO4
*WLN: Not available
*SYNONYMS:
TETRAKISHYDROXYMETHYLPHOSPHONIUM SULFATE
TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULFATE (2:1)
THPS
OCTAKIS(HYDROXYMETHYL)DIPHOSPHONIUM SULFATE
PYROSET TKO
NCI-C55050
-PHYSICAL CHEMICAL DATA
======================
*PHYSICAL DESCRIPTION: LITERATURE: Clear, colorless liquid
REPOSITORY: Clear, colorless viscous liquid
*MOLECULAR WEIGHT: 406.32
*SPECIFIC GRAVITY: Not available
*DENSITY: 1.381 g/cm3 @ 22.2 C (RAD)
*MP (DEG C): -35 C [052]
*BP (DEG C): 111 C [052]
*SOLUBILITIES:
WATER : >=100 mg/mL @ 18 C (RAD)
DMSO : >=100 mg/mL @ 19 C (RAD)
95% ETHANOL : <1 mg/mL @ 19 C (RAD)
METHANOL : <1 mg/mL @ 19 C (RAD)
ACETONE : <1 mg/mL @ 19 C (RAD)
TOLUENE : <1 mg/mL @ 19 C (RAD)
OTHER SOLVENTS: Not available
*VOLATILITY:
Vapor pressure: 32 mm Hg @ 51 C; 150.5 mm Hg @ 73 C [601]
Vapor density : Not available
*FLAMMABILITY(FLASH POINT):
This chemical has a flash point of >93 C (>200 F) (RAD). It is probably
combustible. Fires involving this chemical can be controlled with a dry
chemical, carbon dioxide or Halon extinguisher.
*UEL: Not available LEL: Not available
*REACTIVITY:
This compound is incompatible with oxidizing materials and alkalies [052].
*STABILITY:
This chemical is stable under normal laboratory conditions [052]. Solutions
of this chemical in water, DMSO, 95% ethanol or acetone should be stable for
24 hours under normal lab conditions (RAD).
*OTHER PHYSICAL DATA:
Viscosity: 75 centipoises @ 0 C; 33 centipoises @ 25 C
Vapor pressure: 460.0 mm Hg @ 97 C [601]
-TOXICITY
========
*NIOSH REGISTRY NUMBER: TA2570000
*TOXICITY:
typ. dose mode specie amount units other
Not available
*AQTX/TLM96: Not available
*SAX TOXICITY EVALUATION:
THR = No data.
*CARCINOGENICITY:
Status: NTP Carcinogenesis Studies (Gavage); No Evidence: Male and Female Rat,
Male and Female Mouse [620]
*MUTATION DATA:
test lowest dose | test lowest dose
---------- ---------------- | ---------- -----------------
otr-mus:emb 5000 ppm | otr-ham:kdy 5000 ppm
msc-ham:lng 5000 ppm | msc-mus:lym 6 mg/L
*TERATOGENICITY:
Reproductive Effects Data: Not available
*STANDARDS, REGULATIONS & RECOMMENDATIONS:
OSHA: None
ACGIH: None
NIOSH Criteria Document: None
NFPA Hazard Rating: Health (H): None
Flammability (F): None
Reactivity (R): None
*OTHER TOXICITY DATA:
Status: EPA TSCA Chemical Inventory, 1986
EPA TSCA Test Submission (TSCATS) Data Base, June 1987
-OTHER DATA (Regulatory)
=======================
*PROPER SHIPPING NAME (IATA): Not restricted
*UN/ID NUMBER:
*HAZARD CLASS: SUBSIDIARY RISK: PACKING GROUP:
*LABELS REQUIRED:
*PACKAGING: PASSENGER: PKG. INSTR.: MAXIMUM QUANTITY:
CARGO : PKG. INSTR.: MAXIMUM QUANTITY:
*SPECIAL PROVISIONS:
*USES:
SRI flame retardant for textiles, especially cotton.
*COMMENTS: Not available
-HANDLING PROCEDURES
===================
*ACUTE/CHRONIC HAZARDS:
When heated to decomposition this compound emits very toxic fumes of
phosphorous and sulfur oxides [042]. Decomposition in an aqueous environ-
ment may produce phosphine and formaldehyde [052].
*MINIMUM PROTECTIVE CLOTHING: Not available
*RECOMMENDED GLOVE MATERIALS:
GlovES+ Expert System Glove Types For The Neat (Undiluted) Chemical:
This chemical has not been tested for permeation by Radian Corporation;
however, the GlovES+ expert system was used to extrapolate permeation test
information from compounds in the same chemical class. The GlovES+ system uses
permeation data from literature sources; therefore, extra safety margins should
be used with the estimated protection time(s). If this chemical makes direct
contact with your glove, or if a tear, puncture or hole develops, replace them
at once.
The GlovES+ expert system is a tool that can help people better manage
protection from chemicals, however this tool cannot replace sound judgment nor
make technical decisions. Our GlovES+ expert system is designed to offer
initial advice and assistance in glove selection while the final glove
selection should be made by knowledgeable individuals based on the specific
circumstances involved.
Glove Type Model Number Thickness Estimated Protection Time
Neoprene Comasec Comaprene Unknown 360 min.
Nitrile Comasec Flexatril Unknown 360 min.
PVC Comasec Normal Unknown 360 min.
Butyl rubber North B-161 0.45 mm 360 min.
*RECOMMENDED RESPIRATOR:
Where the neat test chemical is weighed and diluted, wear a NIOSH-
approved half face respirator equipped with an organic vapor/acid gas
cartridge (specific for organic vapors, HCl, acid gas and SO2) with a
dust/mist filter.
*OTHER: Not available
*STORAGE PRECAUTIONS:
You should store this material in a refrigerator.
*SPILLS AND LEAKAGE:
If you should spill this chemical, use absorbent paper to pick up
all liquid spill material. Seal the absorbent paper, as well as any
of your clothing which may be contaminated, in a vapor-tight plastic
bag for eventual disposal. Wash any surfaces you may have contaminated
with a soap and water solution. Do not reenter the contaminated
area until the Safety Officer (or other responsible person) has verified
that the area has been properly cleaned.
*DISPOSAL AND WASTE TREATMENT: Not available
-EMERGENCY PROCEDURES
====================
*SKIN CONTACT:
IMMEDIATELY flood affected skin with water while removing and isolating
all contaminated clothing. Gently wash all affected skin areas thoroughly
with soap and water.
If symptoms such as redness or irritation develop, IMMEDIATELY call a
physician and be prepared to transport the victim to a hospital for treatment.
*INHALATION:
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.
If symptoms (such as wheezing, coughing, shortness of breath, or burning in
the mouth, throat, or chest) develop, call a physician and be prepared to
transport the victim to a hospital.
Provide proper respiratory protection to rescuers entering an unknown
atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA)
should be used; if not available, use a level of protection greater than or
equal to that advised under Respirator Recommendation.
*EYE CONTACT:
First check the victim for contact lenses and remove if present. Flush
victim's eyes with water or normal saline solution for 20 to 30 minutes while
simultaneously calling a hospital or poison control center.
Do not put any ointments, oils, or medication in the victim's eyes without
specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if
no symptoms (such as redness or irritation) develop.
*INGESTION:
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing,
give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a
hospital or poison control center. Be prepared to transport the victim to a
hospital if advised by a physician.
If the victim is convulsing or unconscious, do not give anything by mouth,
ensure that the victim's airway is open and lay the victim on his/her side with
the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport
the victim to a hospital.
*SYMPTOMS:
Symptoms of exposure to this compound include hypotension and general
poisoning [900].
-SOURCES
=======
*SOURCES:
[015] Lewis, R.J., Sr. and R.L. Tatken, Eds. Registry of Toxic Effects
of Chemical Substances. Microfiche Ed. National Institute for
Occupational Safety and Health. Cincinnati, OH. Quarterly
Updates. TA2570000.
[042] Sax, N.I. Dangerous Properties of Industrial Materials. 6th Ed.
Van Nostrand Reinhold. New York. 1984. p. 2541.
[052] Midwest Research Institute. MRI Report for Tetrakis(hydroxymethyl)
phosphonium sulfate. Kansas City, MO. August 31, 1978.
[082] U.S. Environmental Protection Agency, Office of Toxic Substances.
Toxic Substances Control Act Chemical Substance Inventory: 1985
Edition. 5 Vols. U.S. Environmental Protection Agency.
Washington, D.C. January 1986. Listed.
[110] Oak Ridge National Laboratory. Environmental Mutagen Information
Center (EMIC), Bibliographic Data Base. Oak Ridge National
Laboratory. Oak Ridge, TN. Not listed.
[120] Oak Ridge National Laboratory. Environmental Teratogen Information
Center (ETIC), Bibliographic Data Base. Oak Ridge National
Laboratory. Oak Ridge, TN. Not listed.
[601] Safety Consulting Engineers Inc. Vapor Pressure Test Results for
Twelve Materials. Report Number 11053-LR. Safety Consulting
Engineers Inc. Rosemont, IL. August 5, 1988.
[610] Clansky, Kenneth B., Ed. Suspect Chemicals Sourcebook: A Guide to
Industrial Chemicals Covered Under Major Federal Regulatory and
Advisory Programs. Roytech Publications, Inc. Burlingame, CA.
1990. Section 3, p. 158.
[620] United States National Toxicology Program. Chemical Status Report.
NTP Chemtrack System. Research Triangle Park, NC. November 6, 1990.
Listed.
[900] National Library of Medicine. Hazardous Substance Data Base.
Bethesda, MD. March 1, 1982.
-------------------------------------------------------------
---
The Green Chemistry Challenge is a voluntary program that
operates through a broad consortium that includes members of the
chemical industry, trade associations, scientific organizations,
and representatives from academia. The program is open to all
individuals, groups, and organizations involved in chemical
design, manufacture and use.
Additional Information about the Green Chemistry Challenge is
available from EPA's homepage on the internet
(http://www.epa.gov; select "Offices," then "Prevention,
Pesticides, and Toxic Substances," then "Toxics") and from EPA's
Toxic Substance Control Act Assistance Information Service
(202-554-1404; TDD: 202-554-0551), or call EPA's Industrial
Chemistry Branch at 202-260-2659.
_________________________________________________________________
INDEX Award winners are indicated with *.
Advanced Micro Devices (AMD), Austin Environmental Department
The Emission Quantification Model
Albright & Wilson Americas Inc.
Tetrakishydroxymethyl Phosphonium Sulfate (THPS) Biocides
Alliance for Environmental Technology (AET)
The Use of Chlorine Oxide, the Foundation of Elemental
Chlorine-Free Bleaching for Pulp and Paper, as a Pollution
Prevention Process
Altus Biologics Inc.
Cross-Linked Enzyme Crystal Technology
Anderson, Marc A., Water Chemistry Program, University of
Wisconsin-Madison
Green Technology for the 21st Century: Ceramic Membranes
Asarco Incorporated
Asarco -- West Fork Biotreatment Project
Bayer Corporation
Aldimine-Isocyanate Chemistry: a Foundation for
Environmentally-Friendly High Solids Coatings
Benchmark Products, Inc.
Development of a Nickel Brightener Solution
BF Goodrich and Tremco, a BF Goodrich Company
Development of a New Sealant/Adhesive Chemistry for
Automotive Windshields. A New Two Part Chemical System Using
Acetoacetylated Polyol Prepolymers and Aminated
Acetoacetylated Polyol Prepolymers.
BHC Company (Hoechst Celanese Corporation)
The BHC Company Ibuprofen Process
Bureau of Engraving and Printing, Office of Research and
Technical Support
An Alternative Solvent, Isomet
California-Pacific Lab & Consulting
The ECO Funnel
Circuit Research Corporation
A Non-Toxic, Non-Flammable, Aqueous-Based Cleaner/Degreaser
and Associated Parts Washing System Commonly Employed in
Automotive Repair Industry
CTS Corporation Resistor Networks
No-Clean Soldering
DeSimone, Joseph, Department of Chemistry, University of
North Carolina at Chapel Hill, Air Products and Chemicals, Inc.
Soapy CO_2
*Donlar Corporation
*Production and Use of Thermal Polyaspartic Acid
*The Dow Chemical Company
*The Development and Commercial Implementation of 100
Percent Carbon Dioxide as an Environmentally Friendly
Blowing Agent for the Polystyrene Foam Sheet Packaging
Market
The Dow Chemical Company's Novel INVERT(TM) Solvents
Dumesic, James A., Chemical Engineering Department, University of
Wisconsin and John C. Crittenden, National Center for Clean
Industrial and Treatment Technologies, Michigan Technological
University
Rational Design of Catalytic Reactions for Pollution
Prevention
DuPont Company
The DuCare "Zero Effluent" Recycle Chemistry System
The INFINITY Dyeing Process
NAFION Membrane Technology
Eastman Chemical Company
Water-Dispersible Sulfopolyester for Reduced VOC Consumer
Products
Eastman Kodak Company
Polycarbonate/Polydimethylsiloxane Copolymers for Thermal
Print Media
GE Plastics (General Electric Corporation)
New Catalyst for Producing ULTEM(R) Thermoplastic Resin
Hatton, T. Alan, Department of Chemical Engineering,
Massachusetts Institute of Technology, and Stephen L. Buchwald,
Chemistry Department, Massachusetts Institute of Technology
Derivatized and Polymeric Solvents for Minimizing Pollution
during the Synthesis of Pharmaceuticals
Hendrickson, James B., Department of Chemistry, Brandeis
University
The SYNGEN Program for Generation of Alternative Syntheses
Henkel Corporation, Emery Group
Alkyl Polyglycoside Surfactants
*Holtzapple, Mark, Department of Chemical Engineering,
Texas A&M University
*Conversion of Waste Biomass to Animal Feed, Chemicals,
and Fuels
Hudlicky, Tomas, Department of Chemistry, University of Florida
Enzyme-Assisted Conversion of Aromatic Substances to
Value-Added End Products. Exploration of Potential Routes to
Biodegradable Materials and New Pharmaceuticals
Hughes Environmental Systems, Inc.
DryWash(TM)
IBM-Austin
Elimination of Ozone-Depleting Chemicals in the Printed Wire
Board and Electronic Assembly and Test Processes
Innovative Techniques for Chemical and Waste Reductions in
the Printed Wire Board Circuitize Process
Lockheed Martin Tactical Aircraft Systems
Development and Implementation of Low Vapor Pressure
Cleaning Solvent Blends and Waste Cloth Management Systems
to Capture Cleaning Solvent Emissions
Use, Regeneration, and Analysis of Aqueous Alkaline Cleaners
Los Alamos National Laboratory
Application of Freeze Drying Technology to the Separation of
Complex Nuclear Waste
Application of Green Chemistry Principles to Eliminate Air
Pollution from the Mexican Brickmaking Microindustry
Magnetic Separation for Treatment of Radioactive Liquid
Waste
A Microwave Oven Dissolution Procedure for a Ten Gram Sample
of Soil Requiring Radiochemical Analysis
Solvent Replacement and Improved Selectivity in Asymmetric
Catalysis Using Supercritical Carbon Dioxide
Mallinckrodt Chemical, Inc.
The Removal of Oxides of Nitrogen by In Situ Addition of
Hydrogen Peroxide to a Metal Dissolving Process
Merck & Co., Inc.
Waste Minimization in the Manufacture of an Antibiotic
Produced by Chemical Synthesis
Molten Metal Technology, Inc.
Catalytic Extraction Processing
*Monsanto Company
*The Catalytic Dehydrogenation of Diethanolamine
Roundup Ready(TM) Technology
Nalco Chemical Company
Nalco NALMET(R)
Nalco PORTA-FEED(R) Advanced Chemical Handling Systems
Nalco TRASAR(R) Technology
Nalco ULTIMER(TM) Polymer Technology
Nalco Fuel Tech
Nalco Fuel Tech NO_xOUT(R) Process
Paquette, Leo A., Department of Chemistry, Ohio State University
Environmental Advantages Offered by Indium-Promoted
Carbon-Carbon Bond-Forming Reactions in Water
Pharmacia and Upjohn, Inc.
An Alternative Synthesis of Bisnoraldehyde, an Intermediate
to Progesterone and Corticosteroids
Praxair, Inc.
Liquid Oxidation Reactor
Recombinant BioCatalysis, Inc. (RBI)
Development of a Biodiversity Search and Enzyme Optimization
Technology
Rochester Midland Corporation
Development of a New "Core" Line of Cleaners
*Rohm and Haas Company
*Designing an Environmentally Safe Marine Antifoulant
Invention and Commercialization of CONFIRM(TM) Selective
Caterpillar Control Agent
Sandoz Pharmaceutical Corporation
Development of a New Process for the Manufacture of
Pharmaceuticals
Shaw, Henry, Chemistry and Environmental Science Department, New
Jersey Institute of Technology and Dan Watts, Center for
Environmental Engineering and Science, New Jersey Institute of
Technology
The Replacement of Hazardous Organic Solvents with Water in
the Manufacture of Chemicals and Pharmaceuticals
Stanson Corporation
National Conversion to Low Sudsing Hand Dish Detergents for
Industrial, Institutional, and Especially Consumer
Application
Stepan Company
Stepan Company PA Lites Polyester Polyol
Taylor, Larry T., Department of Chemistry, Virginia Tech;
Virginia Tech Intellectual Properties
A Nontoxic Liquid Metal Composition for Use as a Mercury
Substitute
Technic, Inc.; U.S. Department of Energy; and Lawrence Livermore
National Laboratory
Non-Cyanide Silver Electroplating
Texaco Inc.
CleanSystem^3 Gasoline
U.S. Department of Defense, Office of Munitions; U.S. Department
of Energy, Weapons Supported Research; and Lawrence Livermore
National Laboratory
Environmentally-Driven Preparation of Insensitive Energetic
Materials
U.S. Department of Energy, Office of Industrial Technologies
Programs
The Alternative Feedstocks and Biological and Chemical
Technologies Research Programs
U.S. Department of Energy, Office of Pollution Prevention, DOE
Office of Energy Research, DOE Chicago Operations Office, DOE
Argonne Group and Argonne National Laboratory
Application of Microchemistry Technology to the Analysis of
Environmental Samples
U.S. Department of Energy; Pacific Northwest National Laboratory
DOE Methods for Evaluating Environmental and
Waste Management Samples
U.S. Department of Energy; Los Alamos National Laboratory; and
Professor Jonathan Phillips, Department of Chemical Engineering,
Pennsylvania State University
Two-Stage Catalyst for NO_x Reduction, CO Oxidation, and
Hydrocarbon Combustion in Oxygen Containing Exhaust Mixtures
U.S. Department of the Navy, Office of Naval Research; U.S.
Department of the Navy, Naval Surface Warfare Center; Professor
Joseph DeSimone, Department of Chemistry, University of North
Carolina; and Aerojet Propulsion
Use of Carbon Dioxide as an Alternative Green Solvent for
the Synthesis of Energetic Thermoplastic Elastomers
U.S. Department of the Navy, Office of Naval Research; U.S.
Department of the Navy, Naval Surface Warfare Center; U.S. Army
Armament Research, Development and Engineering Center;
Los Alamos National Laboratory; and Aerojet
Waste Reduction in the Production of an Energetic Material
by Development of an Alternative Synthesis
Zeller International
Enviroblock Technology
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