Re: AP story downplays dioxin's link to cancer

["Toxic Discovery Network, Inc." <ToxicDiscovery@email.msn.com>]

I know that vomSaal is here at the Univ. of Missouri in Columbia. Does
anyone in the group have more information that you can provide to us
concerning his research on bis-phenol-A. We do know that bis-phenols were in
the silicone gel that went into breast implants. Any information from any
member to us in private would be helpful.

Thanking you in advance,

Kathy L. Keithley Johnston, R.N.
President/Medical Director

Toxic Discovery Network, Inc.
1906 Grant Lane
Columbia, MO. 65203

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>If I recall, TCDD has been shown or indicated to block some hormone
>mechanism cancers (which also shows it has carcinogenic activity, btw).  I
>suppose it's possible lower exposures may have a protective effect, but I
>have heard several times that low doses tend to promote binding efficiency
>w/ receptor molecules.  vomSaal says this in talking about his extremely
>low doses on bis-phenol-A to rats, chararcterizing higher concentrations as
>"flooding out" the available receptors and shutting down hormonal
>responses/signals (I haven't heard him go into more detail).  Pretty sure I
>recall Devra Lee Davis say (again, generally, or at least in some
>circumstances) that estrogen receptors on breast cells show a greater
>response at low doses.  Well, non of that is directly relevant to the Q. at
>hand!
>
>I notice a lot or many of wire stories about dioxin in recent years, such
>as this one, say dioxin is created in chemical manufacturing, and never
>mention incineration, unless the story is about dioxin from an
>incinerator/boiler.
>
>