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Top EPA Official Says Focus of EPA Endocrine Program Unlikely to Change
>Date: Fri, 15 Aug 1997 14:24:00 -0400 (EDT)
>From: GROUP LIBRARY-HQ 202-260-0748 <LIBRARY-HQ@EPAMAIL.EPA.GOV>
>Subject: Enviro-Newsbrief 08/15/97
>Enviro-Newsbrief August 15, 1997
> The following is a daily update summarizing news of interest
>to EPA staff. It includes information from current news sources:
>newspapers, newsletters, and other publications. For more
>information, contact the EPA Headquarters Information Resources
>Center at (202) 260-5922, or e-mail LIBRARY-HQ.
>**Viewpoints expressed in the following summaries do not
>necessarily reflect EPA policy**
>** ENDOCRINE DISRUPTORS **
>Top EPA Official Says Focus of EPA Endocrine Program Unlikely to
>Change. Inside E.P.A. Weekly Report, August 15, 1997, pp20-21.
> The decision of a leading toxicologist to retract his major
>study on the cumulative effects of "endocrine disruptors"
>will not immediately impact EPA or policy on this topic,
>according to James Aidala, associate administrator for EPA's
>Office of Pesticides, Pollution and Toxic Substances.
> Dr. John McLachan, a former scientific director of the
>National Institute of Environmental Health Studies, did a study
>which concluded that mixtures of chemicals thought to disrupt
>human endocrine systems are more toxic than single chemicals.
>McLachan withdrew his study, claiming he could not reproduce the
>results of the original.
> Aidala said the premise of the study, that combinations of
>chemicals have a synergistic effect on reproductive systems, is
>still a valid theory. "Many people say that if there is all this
>endocrine disruption going on, then we should see it in
>individual chemicals. Well we don't see it. We do not see the
>predicted potencies if you look at these chemicals individually.
>That is why the synergy theory was and still is a good theory.
>But there for a bit, you thought that the work made it more than
>just that, a theory," he said.
> Aidala said the retraction will not affect EPA's work on
>developing screening mechanisms for endocrine disruptors. "The
>fact that he could not replicate it given the context of the
>study does not mean there is not synergy going on out there, it
>just means we have not found it yet."