PCBs: Cancer Dose-Response Assessment and Application to

[ttweed@wildrockies.org (Tony Tweedale)]

>Date: Mon, 4 Nov 1996 09:34:28 -0500
>Reply-To: epa-general@unixmail.rtpnc.epa.gov
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>From: everybody <guest@swais.access.gpo.gov>
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>Subject: PCBs: Cancer Dose-Response Assessment and Application to
>X-Comment: U.S. EPA FEDERAL REGISTER GENERAL documents
>
>[Federal Register: November 4, 1996 (Volume 61, Number 214)]
>[Notices]
>[Page 56680]
>>From the Federal Register Online via GPO Access [wais.access.gpo.gov]
>
>-----------------------------------------------------------------------
>
>ENVIRONMENTAL PROTECTION AGENCY
>[FRL-5646-8]
>
>
>PCBs: Cancer Dose-Response Assessment and Application to
>Environmental Mixtures
>
>AGENCY: Environmental Protection Agency.
>
>ACTION: Notice of availability of final document.
>
>-----------------------------------------------------------------------
>
>SUMMARY: This notice announces the availability of a final report
>titled, PCBs: Cancer Dose-Response Assessment and Application to
>Environmental Mixtures (EPA/600/P-96/001F). The National Center for
>Environmental Assessment (NCEA) of the Office of Research and
>Development developed this report.
>
>ADDRESSES: The document will be available on the Internet at http://
>www.epa.gov/ORD/WebPubs or for purchase from the National Technical
>Information Service, 5285 Port Royal Road, Springfield, VA 22161;
>telephone 703-487-4650; facsimile 703-321-8547. The NTIS order number
>is PB97-104616. Copies will be available for inspection at the U.S.
>Environmental Protection Agency (EPA) headquarters and regional
>libraries and through the U.S. Government Depository Library program.
>The EPA Headquarters Library is located at 401 M Street, S.W.,
>Washington, DC; the library is open Monday through Friday between 10:00
>a.m. and 2:00 p.m., except for Federal holidays.
>
>FOR FURTHER INFORMATION CONTACT: Dr. Jim Cogliano, National Center for
>Environmental Assessment/Washington Office (8602), U.S. Environmental
>Protection Agency, 401 M Street, S.W., Washington, DC 20460. Telephone:
>202-260-3830; facsimile: 202-260-3803; E-mail:
>cogliano.jim@epamail.epa.gov.
>
>SUPPLEMENTARY INFORMATION: The report updates the cancer dose-response
>assessment for polychlorinated biphenyls (PCBs) and shows how
>information on toxicity, disposition, and environmental processes can
>be considered together to evaluate health risks from PCB mixtures in
>the environment. Processes that chemically change PCB mixtures after
>release into the environment need to be considered in assessing the
>mixtures. Thus, guidance is given on applying a range of dose-response
>parameters to different exposure routes, partial lifetime exposure, and
>mixtures of varying composition. Intended to be brief, the document
>focuses on analysis and interpretation rather than a compilation of
>study results. The PCB report was reviewed at a public, external peer
>review workshop in May 1996. The review panel included experts on the
>carcinogenicity of PCBs from the private sector, academia, states, and
>other federal health agencies. This final report has been reviewed and
>approved by EPA's consensus review panel for inclusion on EPA's on-line
>Integrated Risk Information System (IRIS). A revised cancer information
>summary file, reflecting the quantitative and qualitative information
>in the final PCB report, has been loaded onto IRIS.
>
>    Dated: October 22, 1996.
>Robert J. Huggett,
>Assistant Administrator for Research and Development.
>[FR Doc. 96-28242 Filed 11-1-96; 8:45 am]
>BILLING CODE 6560-50-P
>


Tony Tweedale                   || "I'm not going to get involved in any of
Bx 7941                           || that  peer-reviewed mumbo-jumbo."
Missoula, MT 59807     	||           -Rep. John Doolittle (R-CA)
406-542-1709,            ||
fax 728-0867                 ||
ttweed@wildrockies.org   || " 'Are the people being protected?'
			                                    ||   is too narrow a question."
 	                                     	||       -API lobbyists meeting,
12/12/96
              		                        ||
------------------|| "A species becomes extinct every 20 sec's.
Surely one must come into existence every 20 sec's?"
        	-Rep. Helen Chenowith (R-ID)